2 down, 18 down, 13 down, 22 down. Don’t open one’s gin – and not a word! 4 letters, 4 letters, 4 letters and 4 letters.
3 down. Time up: helper needs to change emperor’s habit. 3 letters and 6 letters.
4 down. Rye: mad to introduce the drink cure! 6 letters.
5 down. Amateurish PC met with destruction – it has no application, practically. 4 letters and 11 letters.
6 down. Being a student, inclined to cover only one essential school subject? 8 letters.
7 down. Singers lacking top C – God! 5 letters.
8 down. Civil trade refutes plc. 10 letters.
12 down. Where travellers have a choice of old British soap? 10 letters.
15 down. CERN icy – go mad: “It’s concerning what extreme cold can do!”’. 9 letters.
16 down. Purloin a work of art. 8 letters.
19 down. Arthur dramatically married (no better afterwards). 6 letters.
21 down. Entry of ‘female’ in dictionary rejected by eastern writer. 5 letters.
22 down. See 2.